MPG

Across TCGA pan-cancer cohorts, MPG Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MPG data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher MPG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MPG expression acts as an unfavorable survival marker.

LGG and STAD are the cancer types where MPG Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.021	0.890	<.001	6	view →
STAD	OS	Median	All	0.250	0.729	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MPG–LGG (OS)

Open the LGG breakdown →