MPG

Across TCGA patient cohorts, MPG RNA expression is significantly associated with the mutation status of many other genes, with 9,858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPG-associated genes across cancer lineages are TP53, MGA, and PIK3CA. Each is linked with MPG in more than 6 cancer types. Because this analysis shows association rather than direction, both MPG-to-partner and partner-to-MPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by MPG-low versus MPG-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPG→partner) and Y-score (partner→MPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TP53 →	-1.166	-0.426	<.001	<.001	3	7
STAD	MGA →	+3.321	+0.432	.009	.008	3	4
STAD	PIK3CA →	+2.321	+0.423	<.001	<.001	3	4
STAD	LRBA →	+2.807	+0.435	.003	.005	3	4
UCEC	BICC1 →	+2.747	+0.391	<.001	<.001	3	4
UCEC	LMO7 →	+1.332	+0.470	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,858 associations by consensus.

TP53 by MPG expression — BRCA

Explore this box plot interactively →