MPG

Across TCGA cell cohorts, MPG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,305 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPG-associated GO terms across cancer lineages are Cellular detoxification of methylglyoxal, Cellular response to methylglyoxal, and Response to methylglyoxal. Each is linked with MPG in more than 10 cancer types. Because this analysis shows association rather than direction, both MPG-to-partner and partner-to-MPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular detoxification of methylglyoxal grouped by MPG-low versus MPG-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPG→partner) and Y-score (partner→MPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular detoxification of methylglyoxal →	+0.128	+0.865	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cellular response to methylglyoxal →	+0.128	+0.865	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Response to methylglyoxal →	+0.128	+0.865	<.001	<.001	3	11
SOFT_TISSUE	Metanephric proximal tubule development →	+0.213	+0.733	<.001	<.001	3	10
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.242	+0.856	<.001	<.001	3	10
CNS	Actin filament depolymerization →	+0.198	+0.770	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,305 associations by consensus.

Cellular detoxification of methylglyoxal by MPG expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →