Across TCGA patient cohorts, MPEG1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,120 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MPEG1-associated genes across cancer lineages are BIN2, PIK3R5, and SAMHD1. Each is linked with MPEG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MPEG1-to-partner and partner-to-MPEG1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPEG1→partner) and Y-score (partner→MPEG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BIN2 →	+1.155	+0.522	<.001	<.001	3	6
HNSC	PIK3R5 →	+0.861	+0.562	<.001	<.001	3	6
HNSC	SAMHD1 →	+1.018	+0.508	<.001	<.001	3	5
CCRCC	LILRB5 →	+0.945	+0.603	<.001	<.001	3	5
LSCC	FCRL1 →	+1.260	+0.468	<.001	<.001	3	5
BRCA	PLEKHO2 →	+0.601	+0.514	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,120 associations by consensus.

Exploration

MPEG1 survival (RNA) · tumor vs normal (RNA) · all MPEG1 data types