Across TCGA patient cohorts, MPEG1 mutation is significantly associated with the RNA expression of many other genes, with 2,211 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPEG1-associated genes across cancer lineages are RNU6-1305P, DAPL1, and RN7SKP169. Each is linked with MPEG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MPEG1-to-partner and partner-to-MPEG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPEG1→partner) and Y-score (partner→MPEG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1305P →	+0.277	+4.912	<.001	.005	3	3
UCEC	DAPL1 →	-0.933	-1.716	.003	.004	3	3
DLBC	RN7SKP169 →	+0.284	+4.357	<.001	.004	3	2
DLBC	GNG5P3 →	+0.253	+4.357	<.001	.004	3	2
DLBC	RN7SL736P →	+0.316	+4.655	<.001	.002	3	2
UCEC	LINC02348 →	+0.331	+1.464	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,211 associations by consensus.

Exploration

MPEG1 survival (RNA) · tumor vs normal (RNA) · all MPEG1 data types