MPC2

Across TCGA patient cohorts, MPC2 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPC2-associated genes across cancer lineages are Caspase-7-cleavedD198. Each is linked with MPC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MPC2-to-partner and partner-to-MPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by MPC2-low versus MPC2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPC2→partner) and Y-score (partner→MPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+1.218	+2.827	<.001	.035	2	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Caspase-7-cleavedD198 by MPC2 expression — UCEC

Explore this box plot interactively →