MOV10

Across TCGA patient cohorts, MOV10 mutation is significantly associated with the RNA expression of many other genes, with 951 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOV10-associated genes across cancer lineages are RNA5SP421, RPS29P32, and AGGF1P6. Each is linked with MOV10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MOV10-to-partner and partner-to-MOV10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP421 grouped by MOV10-low versus MOV10-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOV10→partner) and Y-score (partner→MOV10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP421 →	+1.048	+5.438	<.001	.002	3	3
UCEC	RPS29P32 →	+0.390	+2.277	<.001	.003	3	3
LUAD	AGGF1P6 →	+0.234	+5.297	<.001	<.001	3	2
CESC	LINC02559 →	+0.878	+4.342	<.001	.007	3	2
UCEC	PTP4A3 →	-0.902	-3.796	<.001	<.001	3	2
UCEC	NCR1 →	+0.291	+2.946	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 951 associations by consensus.

RNA5SP421 by MOV10 expression — LUSC

Explore this box plot interactively →