MOV10

Across TCGA cell cohorts, MOV10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,088 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MOV10-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of gene expression, epigenetic, and mRNA transport. Each is linked with MOV10 in more than 11 cancer types. Because this analysis shows association rather than direction, both MOV10-to-partner and partner-to-MOV10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by MOV10-low versus MOV10-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOV10→partner) and Y-score (partner→MOV10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Heterochromatin formation →	+0.051	+0.804	<.001	.001	3	12
STOMACH	Negative regulation of gene expression, epigenetic →	+0.060	+0.687	<.001	.006	3	12
BONE	mRNA transport →	+0.089	+0.633	<.001	.001	3	12
BONE	mRNA export from nucleus →	+0.088	+0.633	<.001	.001	3	11
BONE	Nucleic acid transport →	+0.096	+0.564	.003	.006	3	10
BONE	RNA transport →	+0.096	+0.564	.003	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,088 associations by consensus.

Heterochromatin formation by MOV10 expression — LARGE_INTESTINE

Explore this box plot interactively →