MOSPD2

Across TCGA patient cohorts, MOSPD2 mutation is significantly associated with the RNA expression of many other genes, with 3,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOSPD2-associated genes across cancer lineages are IGHD5-12, RN7SKP236, and TUBB4BP7. Each is linked with MOSPD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MOSPD2-to-partner and partner-to-MOSPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD5-12 grouped by MOSPD2-low versus MOSPD2-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOSPD2→partner) and Y-score (partner→MOSPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	IGHD5-12 →	+1.742	+5.421	<.001	.005	3	3
LUAD	RN7SKP236 →	+0.088	+5.108	<.001	.002	3	2
COAD	TUBB4BP7 →	+0.119	+4.037	<.001	.004	3	2
COAD	PSAT1P4 →	+0.518	+4.463	<.001	.002	3	2
READ	APOOP2 →	+0.655	+5.039	<.001	.008	3	2
READ	MIR4710 →	+0.637	+5.219	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,072 associations by consensus.

IGHD5-12 by MOSPD2 expression — READ

Explore this box plot interactively →