Across TCGA patient cohorts, MORN5 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MORN5-associated genes across cancer lineages are Cyclin-E2, EGFR_pY1068, and FASN. Each is linked with MORN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MORN5-to-partner and partner-to-MORN5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN5→partner) and Y-score (partner→MORN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.173	+2.331	.013	.019	3	2
UCEC	EGFR_pY1068 →	-0.205	-2.321	.048	.006	3	1
UCEC	FASN →	+0.402	+3.321	.013	.010	3	1
UCEC	GAPDH →	+0.493	+2.321	.026	.006	3	1
UCEC	Ku80 →	+0.264	+2.013	.006	.016	3	1
UCEC	MEK1 →	+0.470	+3.000	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

MORN5 survival (RNA) · tumor vs normal (RNA) · all MORN5 data types