MORN3

Across TCGA patient cohorts, MORN3 mutation is significantly associated with the RNA expression of many other genes, with 387 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MORN3-associated genes across cancer lineages are PPIAP24, RNA5SP197, and RNU6-634P. Each is linked with MORN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MORN3-to-partner and partner-to-MORN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPIAP24 grouped by MORN3-low versus MORN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN3→partner) and Y-score (partner→MORN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPIAP24 →	+0.179	+2.413	<.001	.005	3	2
COAD	RNA5SP197 →	+0.423	+3.408	.001	.009	3	2
COAD	RNU6-634P →	+0.243	+6.153	<.001	<.001	3	2
COAD	RN7SL98P →	+0.170	+4.693	.003	<.001	3	2
UCEC	MIR4287 →	+0.215	+3.923	<.001	.009	3	2
SKCM	MIR8053 →	+0.227	+4.328	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 387 associations by consensus.

PPIAP24 by MORN3 expression — UCEC

Explore this box plot interactively →