MORF4L1P3

Across TCGA pan-cancer cohorts, MORF4L1P3 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MORF4L1P3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MORF4L1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MORF4L1P3 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and THCA are the cancer types where MORF4L1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MORF4L1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.049	.004	6	view →
KICH	All	All	−0.100	<.001	5	view →
THCA	Male	IV	−0.206	<.001	4	view →
LUSC	Female	All	−0.138	.006	4	view →
LIHC	All	All	+0.035	.002	3	view →
PAAD	All	All	−0.205	.041	2	view →
BRCA	All	III,IV	−0.072	.036	2	view →
KIRP	Male	All	−0.052	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MORF4L1P3–HNSC

Open the HNSC breakdown →