MORC3

Across TCGA cell cohorts, MORC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,259 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MORC3-associated GO terms across cancer lineages are Maintenance of protein location in nucleus, Phosphatidylinositol dephosphorylation, and Maintenance of location. Each is linked with MORC3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MORC3-to-partner and partner-to-MORC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein location in nucleus grouped by MORC3-low versus MORC3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MORC3→partner) and Y-score (partner→MORC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maintenance of protein location in nucleus →	+0.071	+0.719	<.001	.001	3	16
OVARY	Phosphatidylinositol dephosphorylation →	+0.060	+0.837	.001	<.001	3	15
STOMACH	Maintenance of location →	+0.066	+0.590	.004	.003	3	14
OVARY	Phosphatidylinositol biosynthetic process →	+0.056	+0.724	<.001	<.001	3	14
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.143	+0.943	.001	.001	3	14
STOMACH	Phosphatidylinositol metabolic process →	+0.061	+0.862	.006	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

Maintenance of protein location in nucleus by MORC3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →