MORC2-AS1

Across TCGA pan-cancer cohorts, MORC2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MORC2-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MORC2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MORC2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

UCS, BLCA, and HNSC are the cancer types where MORC2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	II,III,IV	0.753	0.289	.001	74	view →
BLCA	DFS	Tertile	III,IV	0.346	0.242	.004	62	view →
HNSC	DFS	Median	All	0.403	0.262	.004	38	view →
KIRP	DFS	Median	IV	0.040	0.524	.006	30	view →
ACC	DFS	Tertile	All	0.218	0.813	.002	23	view →
OV	DFS	Median	II,III,IV	0.123	0.194	.009	20	view →
PAAD	DFS	Quartile	II,III,IV	0.532	0.295	.002	18	view →
SKCM	DFS	Tertile	All	0.254	0.131	.002	14	view →
LGG	OS	Median	All	0.931	0.848	.005	12	view →
THCA	OS	Tertile	All	0.957	1.000	.015	10	view →
READ	OS	Tertile	II,III,IV	0.780	1.000	.015	8	view →
THYM	DFS	Tertile	All	0.964	0.831	.015	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MORC2-AS1–UCS (OS)

Open the UCS breakdown →