MORC1-AS1

Across TCGA pan-cancer cohorts, MORC1-AS1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MORC1-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MORC1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MORC1-AS1 expression acts as an unfavorable survival marker.

THCA, HNSC, and ACC are the cancer types where MORC1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.648	0.939	<.001	75	view →
HNSC	OS	Tertile	II,III,IV	0.219	0.726	<.001	72	view →
ACC	OS	Tertile	All	0.114	0.892	<.001	54	view →
BRCA	DFS	Tertile	II,III,IV	0.729	0.943	<.001	36	view →
BLCA	OS	Tertile	IV	0.250	0.602	.033	18	view →
LIHC	OS	Tertile	III,IV	0.118	0.615	.003	18	view →
SKCM	OS	Tertile	III,IV	0.233	0.705	.034	9	view →
ESCA	OS	Tertile	II,III,IV	0.533	0.732	.018	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
SARC	DFS	Tertile	All	0.223	0.597	.036	9	view →
LGG	OS	Tertile	All	0.571	0.908	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MORC1-AS1–THCA (DFS)

Open the THCA breakdown →