MON2

Across TCGA cell cohorts, MON2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,332 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MON2-associated GO terms across cancer lineages are Protein targeting to vacuole, Positive regulation of organelle assembly, and Early endosome to late endosome transport. Each is linked with MON2 in more than 19 cancer types. Because this analysis shows association rather than direction, both MON2-to-partner and partner-to-MON2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to vacuole grouped by MON2-low versus MON2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MON2→partner) and Y-score (partner→MON2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein targeting to vacuole →	+0.155	+1.302	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.062	+0.980	.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Early endosome to late endosome transport →	+0.063	+0.887	<.001	<.001	3	18
STOMACH	Establishment of protein localization to vacuole →	+0.086	+0.860	<.001	.002	3	17
OESOPHAGUS	Cytosolic transport →	+0.104	+1.352	<.001	.001	3	17
STOMACH	Regulation of TOR signaling →	+0.078	+0.843	.002	.003	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,332 associations by consensus.

Protein targeting to vacuole by MON2 expression — OESOPHAGUS

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