MOK

Across TCGA patient cohorts, MOK protein abundance is significantly associated with the RNA expression of many other genes, with 5,367 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MOK-associated genes across cancer lineages are NUMA1, NADSYN1, and MRPL48. Each is linked with MOK in more than 2 cancer types. Because this analysis shows association rather than direction, both MOK-to-partner and partner-to-MOK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MOK versus NUMA1 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOK→partner) and Y-score (partner→MOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUMA1 →	+0.554	+0.292	<.001	<.001	3	3
LSCC	NADSYN1 →	+0.681	+0.722	.001	.003	3	3
LSCC	MRPL48 →	+0.645	+0.926	.003	<.001	3	3
HNSC	LRTOMT →	+0.837	+0.545	<.001	<.001	3	3
LSCC	ZNF273 →	+0.737	+0.678	<.001	.005	3	3
LSCC	PPME1 →	+0.615	+0.727	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,367 associations by consensus.

MOK vs NUMA1 — HNSC

Explore this scatter interactively →