MOK

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MOK mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MOK-associated genes across cancer lineages are CR1L. Each is linked with MOK in more than 1 cancer types. Because this analysis shows association rather than direction, both MOK-to-partner and partner-to-MOK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CR1L grouped by MOK-low versus MOK-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOK→partner) and Y-score (partner→MOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECR1L →+0.042+4.196.006.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CR1L by MOK expression — LARGE_INTESTINE

Box plot of CR1L in MOK-low vs MOK-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration