MOGS

Across TCGA patient cohorts, MOGS protein abundance is significantly associated with the RNA expression of many other genes, with 14,497 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MOGS-associated genes across cancer lineages are HMOX2, RAB6B, and RAET1E. Each is linked with MOGS in more than 3 cancer types. Because this analysis shows association rather than direction, both MOGS-to-partner and partner-to-MOGS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MOGS versus HMOX2 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOGS→partner) and Y-score (partner→MOGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMOX2 →	-0.811	-0.583	.004	<.001	3	4
LSCC	RAB6B →	+1.716	+0.314	<.001	<.001	3	4
HNSC	RAET1E →	-1.041	-0.313	<.001	.003	3	4
HNSC	TOLLIP →	-0.499	-0.249	<.001	.003	3	4
BRCA	RAB27B →	-1.075	-0.280	<.001	<.001	3	4
UCEC	ITPK1 →	-0.835	-0.634	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,497 associations by consensus.

MOGS vs HMOX2 — UCEC

Explore this scatter interactively →