MOGAT3

Across TCGA cell cohorts, MOGAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,319 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MOGAT3-associated GO terms across cancer lineages are Positive regulation of lipid metabolic process, Positive regulation of triglyceride biosynthetic process, and Regulation of neurotrophin TRK receptor signaling pathway. Each is linked with MOGAT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MOGAT3-to-partner and partner-to-MOGAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lipid metabolic process grouped by MOGAT3-low versus MOGAT3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOGAT3→partner) and Y-score (partner→MOGAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of lipid metabolic process →	+0.064	+0.049	<.001	<.001	3	6
STOMACH	Positive regulation of triglyceride biosynthetic process →	+0.115	+2.246	.001	.001	3	5
LARGE_INTESTINE	Regulation of neurotrophin TRK receptor signaling pathway →	-0.132	-2.092	<.001	<.001	3	5
LARGE_INTESTINE	Alcohol metabolic process →	+0.031	+1.472	<.001	<.001	3	5
STOMACH	Leukocyte mediated cytotoxicity →	+0.134	+1.795	<.001	<.001	3	4
LARGE_INTESTINE	Regulation of immune response to tumor cell →	+0.095	+1.535	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,319 associations by consensus.

Positive regulation of lipid metabolic process by MOGAT3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →