MOGAT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MOGAT2 mutation is significantly associated with the RNA expression of many other genes, with 955 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOGAT2-associated genes across cancer lineages are MIR6803, MIR1302-2HG, and GALNT10. Each is linked with MOGAT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MOGAT2-to-partner and partner-to-MOGAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by MOGAT2-low versus MOGAT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOGAT2→partner) and Y-score (partner→MOGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6803 →+0.150+4.539<.001<.00133
COADMIR1302-2HG →+0.056+4.602<.001.00832
UCECGALNT10 →+0.695+2.606.001.00532
UCECZFYVE19 →+0.341+1.747.004.00432
UCECNCAPH2 →+0.492+2.938<.001<.00132
HNSCSPATA31D4 →+0.024+7.954<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 955 associations by consensus.

MIR6803 by MOGAT2 expression — UCEC

Box plot of MIR6803 in MOGAT2-low vs MOGAT2-high samples in UCEC.

Explore this box plot interactively →

Exploration