Across TCGA patient cohorts, MOG mutation is significantly associated with the RNA expression of many other genes, with 2,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOG-associated genes across cancer lineages are CDKN3, TUBG1, and ENPP2. Each is linked with MOG in more than 2 cancer types. Because this analysis shows association rather than direction, both MOG-to-partner and partner-to-MOG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOG→partner) and Y-score (partner→MOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+0.891	+3.708	<.001	<.001	3	3
UCEC	TUBG1 →	+0.507	+2.823	.004	.001	3	3
SKCM	ENPP2 →	-1.291	-3.687	.001	.001	3	3
SKCM	HES6 →	+0.890	+2.176	.005	.002	3	3
UCEC	WDHD1 →	+0.744	+3.606	<.001	.001	3	3
UCEC	EME1 →	+0.719	+3.180	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,023 associations by consensus.

Exploration

MOG survival (RNA) · tumor vs normal (RNA) · all MOG data types