MOB3A

Across TCGA cell cohorts, MOB3A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,360 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MOB3A-associated GO terms across cancer lineages are Actin filament depolymerization, Protein depolymerization, and Hepatocyte growth factor receptor signaling pathway. Each is linked with MOB3A in more than 10 cancer types. Because this analysis shows association rather than direction, both MOB3A-to-partner and partner-to-MOB3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by MOB3A-low versus MOB3A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB3A→partner) and Y-score (partner→MOB3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.238	+1.010	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Protein depolymerization →	+0.117	+0.892	.003	.001	3	11
CNS	Hepatocyte growth factor receptor signaling pathway →	+0.152	+0.605	<.001	<.001	3	10
LIVER	Positive regulation of focal adhesion assembly →	+0.149	+1.200	<.001	<.001	3	10
LIVER	Protein localization to microtubule plus-end →	+0.241	+1.634	.001	<.001	3	10
LIVER	Protein localization to microtubule end →	+0.241	+1.634	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,360 associations by consensus.

Actin filament depolymerization by MOB3A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →