MOB1AP2

Across TCGA pan-cancer cohorts, MOB1AP2 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MOB1AP2 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MOB1AP2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MOB1AP2 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

OV, STAD, and MESO are the cancer types where MOB1AP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	III,IV	0.614	0.150	.019	90	view →
STAD	DFS	Tertile	II,III,IV	0.196	0.546	<.001	72	view →
MESO	OS	Tertile	All	0.130	0.557	.019	54	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
LAML	DFS	Tertile	All	0.053	0.580	<.001	18	view →
ESCA	DFS	Tertile	III,IV	0.208	0.432	.049	9	view →
SARC	OS	Tertile	All	0.214	0.766	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MOB1AP2–OV (DFS)

Open the OV breakdown →