MNX1-AS1

Across TCGA pan-cancer cohorts, MNX1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MNX1-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MNX1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MNX1-AS1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and READ show a favorable association.

KIRP, KIRC, and THCA are the cancer types where MNX1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.781	0.923	<.001	133	view →
KIRC	DFS	Median	All	0.546	0.706	<.001	96	view →
THCA	DFS	Tertile	All	0.488	0.858	.006	54	view →
LUAD	DFS	Quartile	II,III,IV	0.453	0.636	.009	45	view →
HNSC	OS	Tertile	All	0.478	0.751	<.001	43	view →
UCEC	OS	Tertile	IV	0.325	0.759	.005	32	view →
COAD	DFS	Quartile	II,III,IV	0.354	0.738	.001	28	view →
PCPG	OS	Quartile	All	0.892	1.000	.004	27	view →
ESCA	DFS	Median	All	0.456	0.607	.011	24	view →
CESC	DFS	Median	All	0.435	0.636	.006	20	view →
UVM	OS	Tertile	III,IV	0.215	0.689	.017	18	view →
PAAD	DFS	Tertile	II,III,IV	0.317	0.569	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MNX1-AS1–KIRP (DFS)

Open the KIRP breakdown →