MNT

Across TCGA patient cohorts, MNT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. OV shows the largest number of these associations.

The most reproducible MNT-associated GO terms across cancer lineages are Regulation of cell size, Negative regulation of cell projection organization, and Embryonic appendage morphogenesis. Each is linked with MNT in more than 31 cancer types. Because this analysis shows association rather than direction, both MNT-to-partner and partner-to-MNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell size grouped by MNT-low versus MNT-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MNT→partner) and Y-score (partner→MNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of cell size →	+0.052	+0.699	<.001	<.001	3	32
SCLC	Negative regulation of cell projection organization →	+0.063	+0.876	<.001	.001	3	32
THYM	Embryonic appendage morphogenesis →	+0.047	+0.624	<.001	<.001	3	32
SCLC	Obsolete regulation of histone methylation →	+0.131	+0.820	<.001	<.001	3	32
SCLC	Negative regulation of telomere capping →	+0.102	+0.775	<.001	<.001	3	32
SCLC	Vesicle-mediated transport to the plasma membrane →	+0.055	+0.945	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Regulation of cell size by MNT expression — SCLC

Explore this box plot interactively →