MNDA

Across TCGA patient cohorts, MNDA protein abundance is significantly associated with the RNA expression of many other genes, with 19,562 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MNDA-associated genes across cancer lineages are CYTH4, MEFV, and PLAUR. Each is linked with MNDA in more than 9 cancer types. Because this analysis shows association rather than direction, both MNDA-to-partner and partner-to-MNDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MNDA versus CYTH4 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MNDA→partner) and Y-score (partner→MNDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTH4 →	+1.049	+0.648	<.001	<.001	3	10
LSCC	MEFV →	+1.009	+0.939	<.001	<.001	3	10
GBM	PLAUR →	+1.438	+0.913	<.001	<.001	3	10
HNSC	PLEK →	+1.325	+0.619	<.001	<.001	3	10
GBM	NCF2 →	+1.206	+1.196	<.001	<.001	3	10
GBM	SRGN →	+1.479	+1.249	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,562 associations by consensus.

MNDA vs CYTH4 — HNSC

Explore this scatter interactively →