MNDA

Across TCGA cell cohorts, MNDA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,259 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MNDA-associated GO terms across cancer lineages are Regulation of intracellular transport, Positive regulation of actin filament bundle assembly, and Positive regulation of viral entry into host cell. Each is linked with MNDA in more than 4 cancer types. Because this analysis shows association rather than direction, both MNDA-to-partner and partner-to-MNDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by MNDA-low versus MNDA-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MNDA→partner) and Y-score (partner→MNDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of intracellular transport →	+0.056	+0.052	<.001	<.001	3	5
PANCREAS	Positive regulation of actin filament bundle assembly →	+0.079	+0.038	<.001	.001	3	4
BLOOD_Leukemia	Positive regulation of viral entry into host cell →	+0.098	+2.005	<.001	<.001	3	4
BLOOD_Leukemia	Positive regulation by symbiont of entry into host →	+0.098	+2.005	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Viral budding →	+0.084	+0.037	<.001	.007	3	4
BLOOD_Leukemia	Disruption of cellular anatomical structure in another organism →	+0.532	+2.238	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,259 associations by consensus.

Regulation of intracellular transport by MNDA expression — PANCREAS

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