MND1

Across TCGA pan-cancer cohorts, MND1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MND1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MND1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MND1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, LSCC, and PDAC are the cancer types where MND1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.737	0.298	.009	8	view →
LSCC	DFS	Tertile	All	0.976	0.302	.038	2	view →
PDAC	OS	Median	II,III,IV	1.000	0.812	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MND1–HNSC (DFS)

Open the HNSC breakdown →