MND1

Across TCGA patient cohorts, MND1 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MND1-associated genes across cancer lineages are Mre11, P-Cadherin, and Annexin-1. Each is linked with MND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MND1-to-partner and partner-to-MND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mre11 grouped by MND1-low versus MND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MND1→partner) and Y-score (partner→MND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mre11 →	-0.112	-3.169	.017	.020	3	1
UCEC	P-Cadherin →	-0.169	-3.156	.033	.020	3	1
UCEC	Annexin-1 →	+0.822	+2.827	.004	.035	3	1
UCEC	MEK1 →	+0.536	+3.169	.007	.020	1	1
UCEC	PCNA →	+0.283	+3.169	.017	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Mre11 by MND1 expression — UCEC

Explore this box plot interactively →