MND1

Across TCGA cell cohorts, MND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,337 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MND1-associated GO terms across cancer lineages are DNA replication initiation, Mitotic sister chromatid cohesion, and Attachment of spindle microtubules to kinetochore. Each is linked with MND1 in more than 18 cancer types. Because this analysis shows association rather than direction, both MND1-to-partner and partner-to-MND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by MND1-low versus MND1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MND1→partner) and Y-score (partner→MND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.173	+1.266	.001	.002	3	19
URINARY_TRACT	Mitotic sister chromatid cohesion →	+0.134	+1.155	<.001	<.001	3	18
SOFT_TISSUE	Attachment of spindle microtubules to kinetochore →	+0.146	+1.464	<.001	<.001	3	18
BONE	DNA-templated DNA replication →	+0.119	+1.190	.002	.007	3	18
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.110	+1.585	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.217	+1.224	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,337 associations by consensus.

DNA replication initiation by MND1 expression — BONE

Explore this box plot interactively →