Across TCGA pan-cancer cohorts, MN1 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MN1 data layer compared with 27 for mass-spec protein and 8 for mutation status.
The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MN1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MN1 expression acts as an unfavorable survival marker.
LSCC are the cancer types where MN1 mass-spec protein most reproducibly stratifies survival.