MMUT

Across TCGA pan-cancer cohorts, MMUT mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MMUT data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MMUT mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MMUT expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where MMUT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	1.000	0.825	.017	102	view →
LSCC	OS	Quartile	All	1.000	0.885	.024	14	view →
CCRCC	OS	Tertile	All	1.000	0.887	.015	10	view →
PDAC	OS	Median	III,IV	1.000	0.589	.023	10	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MMUT–COAD (DFS)

Open the COAD breakdown →