MMS22L

Across TCGA patient cohorts, MMS22L protein abundance is significantly associated with the RNA expression of many other genes, with 9,879 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MMS22L-associated genes across cancer lineages are CDCA8, CENPM, and CENPF. Each is linked with MMS22L in more than 4 cancer types. Because this analysis shows association rather than direction, both MMS22L-to-partner and partner-to-MMS22L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMS22L versus CDCA8 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMS22L→partner) and Y-score (partner→MMS22L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDCA8 →	+1.377	+0.519	.001	.002	3	5
GBM	CENPM →	+1.454	+0.896	.003	.009	3	4
GBM	CENPF →	+1.565	+0.645	.001	.006	3	4
GBM	PIMREG →	+1.878	+0.921	.003	.007	3	4
GBM	DTL →	+1.653	+0.916	.005	.007	3	4
GBM	CHEK1 →	+1.605	+0.923	.004	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,879 associations by consensus.

MMS22L vs CDCA8 — OV

Explore this scatter interactively →