MMS22L

Across TCGA cell cohorts, MMS22L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,481 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MMS22L-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Mitotic nuclear division, and DNA strand elongation. Each is linked with MMS22L in more than 19 cancer types. Because this analysis shows association rather than direction, both MMS22L-to-partner and partner-to-MMS22L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by MMS22L-low versus MMS22L-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMS22L→partner) and Y-score (partner→MMS22L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of cell cycle process →	+0.073	+1.313	.001	<.001	3	20
BLOOD_Lymphoma	Mitotic nuclear division →	+0.099	+1.500	<.001	<.001	3	20
BONE	DNA strand elongation →	+0.215	+1.519	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.140	+1.374	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome organization →	+0.106	+1.543	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.142	+1.582	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,481 associations by consensus.

Negative regulation of cell cycle process by MMS22L expression — BLOOD_Myeloma

Explore this box plot interactively →