MMRN2

Across TCGA pan-cancer cohorts, MMRN2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MMRN2 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MMRN2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MMRN2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where MMRN2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	III,IV	0.858	0.534	.011	12	view →
LUAD	DFS	Tertile	III,IV	0.292	0.944	.001	12	view →
UCEC	DFS	Median	II,III,IV	0.536	0.880	.044	8	view →
HNSC	OS	Median	II,III,IV	0.953	1.000	.019	4	view →
LSCC	DFS	Quartile	II,III,IV	0.812	1.000	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MMRN2–CCRCC (OS)

Open the CCRCC breakdown →