MMRN2

Across TCGA patient cohorts, MMRN2 mutation is significantly associated with the RNA expression of many other genes, with 3,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MMRN2-associated genes across cancer lineages are MIR4684, UHRF1, and MAX. Each is linked with MMRN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MMRN2-to-partner and partner-to-MMRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4684 grouped by MMRN2-low versus MMRN2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMRN2→partner) and Y-score (partner→MMRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4684 →	+0.558	+5.103	<.001	.008	3	3
UCEC	UHRF1 →	+0.859	+2.148	<.001	<.001	3	3
STAD	MAX →	+0.368	+3.207	.005	.009	3	3
BLCA	RNU4-15P →	+0.398	+5.147	<.001	.003	3	3
UCEC	SUPV3L1 →	+0.331	+2.742	.005	.002	3	3
UCEC	TYW3 →	+0.430	+2.463	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

MIR4684 by MMRN2 expression — CESC

Explore this box plot interactively →