MMRN1

Across TCGA pan-cancer cohorts, MMRN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MMRN1 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MMRN1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MMRN1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where MMRN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.333	0.811	<.001	37	view →
PDAC	OS	Median	II,III,IV	0.426	0.614	.010	12	view →
CCRCC	DFS	Tertile	IV	0.784	0.138	.024	7	view →
HNSC	OS	Median	All	0.956	1.000	.014	6	view →
LSCC	DFS	Tertile	II,III,IV	0.848	1.000	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MMRN1–LUAD (OS)

Open the LUAD breakdown →