MMRN1

Across TCGA cell cohorts, MMRN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 888 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MMRN1-associated GO terms across cancer lineages are Negative regulation of neurotransmitter uptake, Negative regulation of serotonin uptake, and Negative regulation of dopamine metabolic process. Each is linked with MMRN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MMRN1-to-partner and partner-to-MMRN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of neurotransmitter uptake grouped by MMRN1-low versus MMRN1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMRN1→partner) and Y-score (partner→MMRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of neurotransmitter uptake →	+0.874	+1.471	<.001	<.001	3	5
BLOOD_Leukemia	Negative regulation of serotonin uptake →	+0.874	+1.471	<.001	<.001	3	5
URINARY_TRACT	Negative regulation of dopamine metabolic process →	+0.265	+0.030	.002	.002	3	4
KIDNEY	Synaptic transmission, dopaminergic →	+1.610	+0.046	<.001	.004	3	4
BLOOD_Leukemia	Synaptic vesicle recycling →	+0.034	+1.070	.006	.005	3	4
BLOOD_Leukemia	Dopamine uptake involved in synaptic transmission →	+1.353	+2.005	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 888 associations by consensus.

Negative regulation of neurotransmitter uptake by MMRN1 expression — BLOOD_Leukemia

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