MMRN1

Across TCGA cell cohorts, MMRN1 mutation is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MMRN1-associated genes across cancer lineages are CFHR5, INIP, and C3orf38. Each is linked with MMRN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMRN1-to-partner and partner-to-MMRN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR5 grouped by MMRN1-low versus MMRN1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMRN1→partner) and Y-score (partner→MMRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CFHR5 →	+0.048	+3.736	<.001	.003	3	2
LUNG_NSCLC_LUAD	INIP →	+0.494	+3.206	.009	.006	3	2
LUNG_NSCLC_LUAD	C3orf38 →	+0.474	+3.206	.006	.006	3	2
LARGE_INTESTINE	USP18 →	+1.238	+3.523	<.001	<.001	3	2
LUNG_NSCLC_LUAD	TRIM49C →	+0.015	+2.343	.001	.008	3	2
LUNG_NSCLC_LUAD	DPRX →	+0.105	+3.006	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

CFHR5 by MMRN1 expression — LUNG_SCLC

Explore this box plot interactively →