MMP7

Across TCGA cell cohorts, MMP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,449 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MMP7-associated GO terms across cancer lineages are Antigen processing and presentation, Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, and Positive regulation of iron ion transport. Each is linked with MMP7 in more than 11 cancer types. Because this analysis shows association rather than direction, both MMP7-to-partner and partner-to-MMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation grouped by MMP7-low versus MMP7-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP7→partner) and Y-score (partner→MMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Antigen processing and presentation →	+0.118	+3.632	<.001	.001	3	12
BREAST	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	+0.055	+2.501	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of iron ion transport →	+1.360	+4.069	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of iron ion transmembrane transport →	+1.360	+4.069	<.001	<.001	3	11
PANCREAS	Regulation of adaptive immune response →	+0.056	+4.871	.002	<.001	3	10
PANCREAS	Basement membrane disassembly →	+1.281	+3.728	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,449 associations by consensus.

Antigen processing and presentation by MMP7 expression — PANCREAS

Explore this box plot interactively →