MMP7

Across TCGA cell cohorts, MMP7 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MMP7-associated genes across cancer lineages are C1orf87, TEX43, and OR10W1. Each is linked with MMP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMP7-to-partner and partner-to-MMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by MMP7-low versus MMP7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP7→partner) and Y-score (partner→MMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C1orf87 →	+0.025	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	IL36B →	+0.032	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR5P2 →	+0.032	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

C1orf87 by MMP7 expression — BLOOD_Leukemia

Explore this box plot interactively →