MMP28

Across TCGA cell cohorts, MMP28 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,306 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MMP28-associated GO terms across cancer lineages are Pressure natriuresis, Positive regulation of protein localization to cell periphery, and Meiotic sister chromatid cohesion. Each is linked with MMP28 in more than 8 cancer types. Because this analysis shows association rather than direction, both MMP28-to-partner and partner-to-MMP28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pressure natriuresis grouped by MMP28-low versus MMP28-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP28→partner) and Y-score (partner→MMP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Pressure natriuresis →	+1.188	+2.151	<.001	<.001	3	9
STOMACH	Positive regulation of protein localization to cell periphery →	+0.140	+2.305	<.001	.001	3	9
STOMACH	Meiotic sister chromatid cohesion →	-0.096	-1.899	.009	.003	3	8
PANCREAS	Homophilic cell-cell adhesion →	+0.142	+2.197	<.001	.006	3	8
STOMACH	Regulation of striated muscle contraction →	+0.114	+1.871	<.001	<.001	3	8
PANCREAS	Leukotriene B4 catabolic process →	+1.569	+4.227	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,306 associations by consensus.

Pressure natriuresis by MMP28 expression — STOMACH

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