MMP27

Across TCGA patient cohorts, MMP27 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,057 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MMP27-associated GO terms across cancer lineages are Cellular oxidant detoxification, Cellular response to starvation, and Cellular response to type II interferon. Each is linked with MMP27 in more than 15 cancer types. Because this analysis shows association rather than direction, both MMP27-to-partner and partner-to-MMP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular oxidant detoxification grouped by MMP27-low versus MMP27-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP27→partner) and Y-score (partner→MMP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular oxidant detoxification →	+0.052	+0.105	<.001	<.001	3	16
STAD	Cellular response to starvation →	+0.053	+0.098	<.001	<.001	3	15
STAD	Cellular response to type II interferon →	+0.051	+0.110	<.001	<.001	3	15
ESCA	Lamellipodium organization →	+0.057	+0.162	.001	.002	3	14
STAD	Detoxification →	+0.046	+0.116	<.001	<.001	3	14
STAD	Respiratory system development →	+0.044	+0.082	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,057 associations by consensus.

Cellular oxidant detoxification by MMP27 expression — STAD

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