MMP27

Across TCGA cell cohorts, MMP27 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,325 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MMP27-associated GO terms across cancer lineages are IMP biosynthetic process, Regulation of CD8-positive, alpha-beta T cell extravasation, and Calcium-dependent cell-cell adhesion. Each is linked with MMP27 in more than 5 cancer types. Because this analysis shows association rather than direction, both MMP27-to-partner and partner-to-MMP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by MMP27-low versus MMP27-high in OVARY.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP27→partner) and Y-score (partner→MMP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IMP biosynthetic process →	+0.251	+1.774	<.001	.001	3	6
BONE	Regulation of CD8-positive, alpha-beta T cell extravasation →	+0.263	+1.337	.007	.004	3	6
LUNG_NSCLC_LUAD	Calcium-dependent cell-cell adhesion →	-0.265	-1.065	.001	.002	3	5
LUNG_NSCLC_LUAD	UDP-galactose transmembrane transport →	-0.137	-1.220	<.001	.001	3	5
BLOOD_Lymphoma	Regulation of entry of bacterium into host cell →	+0.270	+1.205	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Ribonucleoside metabolic process →	+0.202	+0.712	.009	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,325 associations by consensus.

IMP biosynthetic process by MMP27 expression — OVARY

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