MMP24OS

Across TCGA pan-cancer cohorts, MMP24OS mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MMP24OS data layer compared with 24 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher MMP24OS mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MMP24OS expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

GBM, CCRCC, and UCEC are the cancer types where MMP24OS mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.391	0.736	.016	9	view →
CCRCC	DFS	Tertile	II,III,IV	0.517	0.835	.015	7	view →
UCEC	DFS	Quartile	All	0.963	0.783	.018	6	view →
PDAC	OS	Median	III,IV	0.792	0.318	.024	6	view →
LSCC	DFS	Median	All	0.893	0.975	.026	2	view →
LUAD	OS	Tertile	All	0.707	0.959	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MMP24OS–GBM (OS)

Open the GBM breakdown →