Across TCGA patient cohorts, MMP23B protein abundance is significantly associated with the RNA expression of many other genes, with 7,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MMP23B-associated genes across cancer lineages are NALCN, FHL5, and DCN. Each is linked with MMP23B in more than 3 cancer types. Because this analysis shows association rather than direction, both MMP23B-to-partner and partner-to-MMP23B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP23B→partner) and Y-score (partner→MMP23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NALCN →	+0.576	+0.695	<.001	<.001	3	3
LSCC	FHL5 →	+1.016	+0.585	<.001	<.001	3	3
OV	DCN →	+1.683	+0.832	.002	.004	3	3
OV	CNRIP1 →	+1.320	+1.230	<.001	<.001	3	3
OV	KLF2 →	+1.102	+0.871	.003	.007	3	3
OV	CDO1 →	+1.441	+1.183	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,839 associations by consensus.

Exploration

MMP23B survival (RNA) · tumor vs normal (RNA) · all MMP23B data types