MMP2

Across TCGA patient cohorts, MMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,064 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MMP2-associated genes across cancer lineages are PCOLCE, AEBP1, and TGFB3. Each is linked with MMP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MMP2-to-partner and partner-to-MMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMP2 versus PCOLCE in OV, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP2→partner) and Y-score (partner→MMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+1.438	+0.870	<.001	<.001	3	10
OV	AEBP1 →	+2.561	+0.984	<.001	<.001	3	10
OV	TGFB3 →	+1.530	+1.026	<.001	<.001	3	10
OV	PTGIS →	+1.636	+1.084	<.001	<.001	3	10
UCEC	RHOJ →	+0.839	+0.595	<.001	<.001	3	10
OV	POSTN →	+3.269	+0.917	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,064 associations by consensus.

MMP2 vs PCOLCE — OV

Explore this scatter interactively →