MMP2

Across TCGA cell cohorts, MMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,599 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MMP2-associated GO terms across cancer lineages are Luteinization, Trophoblast cell migration, and Ovulation from ovarian follicle. Each is linked with MMP2 in more than 17 cancer types. Because this analysis shows association rather than direction, both MMP2-to-partner and partner-to-MMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Luteinization grouped by MMP2-low versus MMP2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP2→partner) and Y-score (partner→MMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Luteinization →	+1.693	+3.178	<.001	<.001	3	18
LIVER	Trophoblast cell migration →	+0.316	+4.764	.004	.003	3	15
SOFT_TISSUE	Ovulation from ovarian follicle →	+1.653	+5.342	<.001	<.001	3	14
OESOPHAGUS	Establishment of apical/basal cell polarity →	+0.150	+2.338	.004	.005	3	12
BONE	Collagen metabolic process →	+0.245	+4.260	<.001	<.001	3	12
BONE	Regulation of mesenchymal stem cell proliferation →	+0.239	+4.000	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,599 associations by consensus.

Luteinization by MMP2 expression — URINARY_TRACT

Explore this box plot interactively →