Across TCGA patient cohorts, MMP17 protein abundance is significantly associated with the RNA expression of many other genes, with 1,685 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MMP17-associated genes across cancer lineages are NEFH, SYNGR1, and PNPLA5. Each is linked with MMP17 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMP17-to-partner and partner-to-MMP17 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP17→partner) and Y-score (partner→MMP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEFH →	+1.018	+0.510	<.001	<.001	3	1
GBM	SYNGR1 →	+0.650	+0.421	.001	.001	3	1
GBM	PNPLA5 →	+0.271	+0.466	<.001	<.001	3	1
GBM	PVALB →	+0.832	+0.441	.002	.007	3	1
GBM	COCH →	+0.421	+0.387	.007	.002	3	1
GBM	CHGA →	+1.383	+0.527	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,685 associations by consensus.

Exploration

MMP17 survival (RNA) · tumor vs normal (RNA) · all MMP17 data types